2934: GLP-1 Drugs Are Killing People — Here Is What Nobody Is Telling You
Aug 29, 2026
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In this episode the guys break down the dangers of GLP-1 drugs — covering who they are actually for, who they are not for, the real risks including muscle loss, bone density decline and gastroparesis, and the only right way to use them with resistance training and behavioral change. They also get into Sal’s Collective shoes situation that led into an unexpected swinger conversation, the new federal income brackets and what it says about inflation, why owning a home is quietly becoming a luxury not a right, a massive 236-country demographic study showing global fertility has fallen below replacement rate for the first time in 60,000 years, why going to church is the biggest predictor of economic upward mobility, and the guys sharing their personal Caldera Lab favorites. Then they coach live callers submitted through mplivecaller.com.
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0:00 – Intro
2:09 – GLP-1 drugs are killing people — and they’re not the panacea everyone thinks
5:17 – Who GLP-1 is actually for and who is using it wrong
11:44 – The risks: muscle loss, bone density, gastroparesis and behavioral dependency
16:14 – The only right way to use GLP-1 — resistance training, protein and behavior change
27:58 – Sal’s Collective shoes situation — and the unexpected swinger conversation
37:24 – New federal income brackets and what they reveal about real inflation
41:00 – Why owning a home is quietly becoming a luxury rather than a right
48:10 – 236-country study: global fertility below replacement rate for the first time in 60,000 years
51:18 – Church attendance as the single biggest predictor of economic upward mobility
54:30 – The guys share their personal Caldera Lab favorites
1:11:40 – Caller: Kennedy (Missouri) — returning caller, up from 1,600 to 2,800 calories, strength gains
1:21:24 – Caller: RSI (Colorado) — 6-7 years lifting, approaching intermediate plateau, needs a program change
1:29:48 – Caller: Autumn (Ohio) — no lower body strength progress in 2 years after a lean phase
1:37:10 – Caller: Hunter (Utah) — training around a recurring injury, wants to stay consistent
